The FGC has purchased the Ambion® Complete Human Genome Silencer® Select siRNA library. This library contains three constructs per target (64,752 constructs). The Ambion Silencer Select siRNAs are designed using their most advanced algorithm developed using a machine learning approach. In addition the siRNAs are chemically modified to enhance guide strand bias. This has the effect of maximizing siRNA silencing potency and for decreasing passenger strand related off-target effects. We will be happy to work with you to optimize the transfection protocols for your system and perform screens of the full genome or smaller sets.