Functional Genomics Core COVID-19 Continuity of Operations

The University of Arizona is committed to:

  • The health and safety of students, faculty, staff, researchers and designated campus colleagues
  • The continuity of research operations with modifications to observe CDC guidelines to minimize disease transmission
  • Ensuring laboratory safety that minimizes risk to human and animal subjects

The following guidelines apply to all University of Arizona core facilities, shared resource centers,and labs(facilities)and for all users regardless of purpose (basic research, product development, etc.). Individual facilities may exercise more restrictive and customized protocols that reflect their unique conditions but must follow these minimal guidelines and precautionary measures.

General Practices

  • Stay informed and follow all policy and guidance updates from CDC, UA, and RII at the UA Coronavirus/COVID-19 resource website and the RII Research Specific Coronavirus COVID-19 Information website. Refer to individual facility websites for updated information and specific protocols.
  • Minimize the number of people coming to campus and using campus facilities. Employees who are able to perform their duties remotely without disrupting continuity of operations should do so. No employee who has expressed a preference to work off-site should feel pressured to work on campus.
  • For research that continues, every reasonable accommodation will be made to provide access to core facilities instrumentation, services, and personnel within these generalized guidelines and facility-specific protocols. Depending on the facility, there may be reduced hours of operation and staff that will delay normal access and extend turn-around times for services. Check the individual facility website for information on current operational continuity updates.
  • Business services associated with iLab Core Facilities will maintain continuity of operations as normal.
  • Essential facilities infrastructure (e.g. power, telecommunications, HVAC) will be maintained.
  • Facility managers have the authority to refuse entry or suspend user activities if these guidelines or specific facility protocols are not followed.

Facility Access

  • Employees who self-recognize symptoms,or have someone in their household with symptoms, should not come to work. If symptoms are recognized in an individual (CDC guidance), facility managers/staff should send that individual home. Researchers, patients, students, post-docs, and other users who show symptoms, or have someone in their household with symptoms,should not enter the facility. Facility managers/staff should assess the risk level of users before they enter the facility and send them homeif symptoms are recognized(CDC guidance).
  • Normal after-hours access to facilities may be discontinued unless safety/cleaning protocols have been established. Check the individual facility website for updated information.
  • Distinguish and separate functions that require presence in the facility (e.g. data generation) from those that can be done remotely (e.g. data analysis).

Social Distancing

  • All individuals in the FGC are expected to wear a face mask
  • All labs/core facilities should follow social distancing standards, e.g. maintain 6’ between individuals.
  • Conduct meetings via tele-conference or video-conference using online platforms.
  • Facility user capacity should be determined by social distancing standards. Depending on the facility,this may require staggered or reduced scheduling or limiting instrument use to one person at a time.
  • Assisted-use instrumentation and in-person user trainings/workshops are discouraged. If the research can’t be postponed, researchers/PIs should work with the facility manager to explore alternative options in lieu of close distances inherent with these activities (e.g. virtual assistance, direct sample submission, etc.).

Cleaning

  • Facility staff should wash their hands hourly following CDC hand washing guidelines.
  • Facility users should wash their hands immediately before and after their time in the facility following CDC hand washing guidelines.
  • Common touch-point surfaces (keyboards, door handles, touchscreens, chairs, etc.)should be decontaminated by facility staff daily following CDC guidelines.
  • Instrumentation should be decontaminated after each use. This should be done by facility staff, unless specific facility decontamination protocols dictate otherwise.
  • Physical artifacts of facility operations that exchange hands (receipts, documents, shop drawings, etc.) should be avoided and digital versions should be used instead. Physical sample submissions should be handled with gloves.

Our Mission

The Functional Genomics Core’s mission is to provide researchers at the University of Arizona with the capacity to run high-throughput compoundRNAi, and deletion library based screens for the purpose of network analysis, drug and/or target discovery.  We will work with you to develop an assaycarryout a screen and/or analyze the data.  The equipment in the laboratory is also available for general (low-throughput) use.

Our facility is setup in a modular fashion to ensure flexibility. We will develop a custom pipeline to meet your research goals.

Our Biomek FX liquid handling workstation with an integrated Liconic shaker incubator (temperature, humidity, and CO2 controlled) can be used to setup and grow most cell types in 96 well plates. This robot is equipped to add RNAi constructs, drugs or other stimuli to each plate. The Biomek FX can also be used to perform high-throughput biochemical assays. Cell based assays can be carried out using either the Operetta CLS  high-content analysis system or the Attune Acoustic Focusing Flow Cytometer. Both instruments have powerful, but easy to use software for data analysis.

Looking for a different core? Try University of Arizona Cores and Shared Services


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