Instruments

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CLARIOstarPlus

The CLARIOstar Plus is both the most flexible and sensitive microplate reader on the market. The CLARIOstar Plus has patented Linear Variable Filters that allow the user to select their ideal wavelengths with the provided and supported software, allowing for excitation and emission reads over multiple wavelengths without hardware manipulations. The CLARIOstar Plus is able to perform modern cell/molecular/high throughput assays (e.g., Bioluminescent Resonance Energy Transfer (BRET), nanoBRET, Time Resolved Fluorescence (TRF); Homogenous TRF, AlphaScreen®; Fluorescence Polarization and Long Term Kinetic Live Cell Assays).

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The Octet RED384 is a non-fluorescence-based, high-throughput, bench top, protein interaction detection system that uses Bio-Layer Interferometry (BLI) technology, and can analyze up to 16 samples in parallel for affinity, kinetics or active protein concentration determination from samples in 96- or 384-well microplates. 

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operetta cls

The Operetta CLS is a high-content analysis microscope imaging system. It is designed to characterize fine cellular details. The Operetta conducts fully-automated high-capacity, quantitative cellular analysis of fixed or live cells. It contains a highly sensitive sCMOS camera that provides a large field of view and high resolution image capture. The Operetta's Harmony software automates complex phenotypic analysis.

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The FGC has two Dual arm Biomek FX liquid handling automation systems. The primary system is equipped with both a Liconic STX-44 live cell incubator and a large capacity Cytomat ambient storage hotel. The Liconic STX-44 incubator has temperature control, humidity control, CO2 control and can shake up to 1200 RPM. This incubator is capable of meeting the needs of most cell types for live cell screening. This system is also equipped with a detachable compound pinning tool, sonicating wash station, and pin drying fan. This robot can perform precision pipetting down to 0.2 µl and precision pinning down to 10 nl.

The second Dual arm Biomek FX liquid handeling automation system is equipped with both a large capacity incubated Cytomat storage hotel and and a large capacity Cytomat ambient storage hotel. This system is configured to perform a wide array of liquid handling operations. Both systems can perform high-throughput cherrypicking and plate refactoring, dilution and normalization, and the automation of most molecular biology protocols.

More information about RNAi screening

More information about Drug screening

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The Singer RoToR HDA pinning robot is a dedicated system for pinning arrays of yeast and bacteria. It is designed for rapid replication, arraying, mating and breakdown at 96, 384, 768 and 1536 density of yeast or bacteria libraries from one (or multiple) source plate(s) to one (or multiple) target plate(s) on agar or in liquid medium.

A Singer Rotor pinning robot is available for pinning arrays of yeast or other microbes. This instrument is used to cross thousands of yeast strains to aid in yeast two hybrid screening, creation of novel yeast libraries, or replication of bacterial libraries.

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